Project Workplace Integrated Support and Education (WISE) is developed as an e-learning training program in suicide safety planning combined with skill-building Web technologies for integration into the routine workflow of nurses serving medical, surgical or traumatically injured patients. The effort targets two common obstacles to effective continuing education and the application of training knowledge to healthcare practice: the need for efficient, low-cost training that fosters suicide-prevention skills and the scarcity of efficient quality-evaluation tools for trainee suicide-prevention skills for both training and skill maintenance. Project WISE's e-learning training component is followed by a half-hour role-play practice with the Client Bot conversational agent. Following this is a practice session with an actor playing a medically hospitalized patient at suicide risk. Project WISE includes developmental and pilot research to direct the refinement and implementation of e-learning training along with the design of a future large-scale practical trial. The authors note they expect "much will be learned about suicide prevention with hospitalized patients, the role of nurses in this work and how nurses engage with novel training technologies. As such, Project WISE is expected to help further the national agenda of implementing suicide prevention in healthcare settings and inform best practices for meeting the needs for provider training that will be required to reach this goal."